Cldn13 | claudin 13

GeneMGI:1913102Synonyms: 2500004B14Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

46Embryo tissues

Phenotypes

Allele:

Phy. System:

Life Stage:



abnormal startle reflex	1 supporting dataset	Cldn13^em1(IMPC)J	homozygote	Late adult	5.15x10^-5
increased circulating potassium level	1 supporting dataset	Cldn13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.09x10^-5
increased hemoglobin content	1 supporting dataset	Cldn13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.51x10^-5
decreased mean corpuscular volume	1 supporting dataset	Cldn13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.27x10^-6
increased circulating sodium level	1 supporting dataset	Cldn13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.95x10^-5
decreased grip strength	1 supporting dataset	Cldn13^em1(IMPC)J	homozygote	Early adult	2.3x10^-5
abnormal coat/hair pigmentation	6 supporting datasets	Cldn13^em1(IMPC)J	homozygote	Late adult	8.43x10^-11
persistence of hyaloid vascular system	1 supporting dataset	Cldn13^em1(IMPC)J	homozygote	Early adult	1.51x10^-5
increased erythrocyte cell number	1 supporting dataset	Cldn13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.56x10^-7
increased circulating alanine transaminase level	1 supporting dataset	Cldn13^em1(IMPC)J	homozygote	Late adult	7.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cldn13.

Associated images

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Histopathology

There is no histopathology data found for Cldn13.

IMPC related publications

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External links

No external links available for Cldn13.

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*Cldn13^em1(IMPC)J*	Indel	‌	mouse
*Cldn13^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Cldn13^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Cldn13^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cldn13^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cldn13^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Cldn13^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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