Hnrnph1 | heterogeneous nuclear ribonucleoprotein H1

GeneMGI:1891925Synonyms: Hnrph1, E430005G16Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetHnrnph1tm1b(KOMP)WtsiheterozygoteEarly adult1.08x10-18 
increased lymphocyte cell number2 supporting datasetsHnrnph1tm1b(KOMP)WtsiheterozygoteEarly adult2.6x10-7 
increased mean corpuscular volume1 supporting datasetHnrnph1tm1b(KOMP)WtsiheterozygoteEarly adult6.16x10-26 
preweaning lethality, complete penetrance1 supporting datasetHnrnph1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased mean platelet volume1 supporting datasetHnrnph1tm1b(KOMP)WtsiheterozygoteEarly adult2.74x10-5 
decreased neutrophil cell number1 supporting datasetHnrnph1tm1b(KOMP)WtsiheterozygoteEarly adult8.04x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hnrnph1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Hnrnph1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Hnrnph1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Hnrnph1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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