Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

GeneMGI:1891917Synonyms: 14-3-3b, 14-3-3 beta, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.12x10^-18
decreased circulating iron level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.96x10^-5
decreased circulating total protein level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.1x10^-6
decreased blood urea nitrogen level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.24x10^-6
decreased total retina thickness	2 supporting datasets	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.7x10^-21
abnormal behavior	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.76x10^-5
thrombocytopenia	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.18x10^-7
decreased circulating triglyceride level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.62x10^-5
decreased circulating cholesterol level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.45x10^-7
increased circulating bilirubin level	1 supporting dataset	Ywhab^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.56x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ywhab.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ywhab.

IMPC related publications

Loading...

External links

No external links available for Ywhab.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ywhab^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ywhab^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes