Gde1 | glycerophosphodiester phosphodiesterase 1

GeneMGI:1891827Synonyms: MIR16, 1200003M13Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal behavior	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.36x10^-6
decreased vertical activity	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.21x10^-5
decreased startle reflex	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.26x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.52x10^-5
abnormal gait	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.04x10^-5
increased circulating cholesterol level	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.32x10^-6
increased vertical activity	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.2x10^-5
abnormal behavior	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.54x10^-17
prolonged QRS complex duration	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.52x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Gde1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gde1.

Associated images

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Histopathology

There is no histopathology data found for Gde1.

IMPC related publications

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External links

No external links available for Gde1.

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*Gde1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Gde1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gde1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Gde1^{tm47313(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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