Brat1 | BRCA1-associated ATM activator 1

GeneMGI:1891679Synonyms: Baat1

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Embryo Growth/size/body region Mortality/aging

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Brat1^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal placenta size	1 supporting dataset	Brat1^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal embryo size	1 supporting dataset	Brat1^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal embryo size	1 supporting dataset	Brat1^em1(IMPC)Bay	heterozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Brat1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brat1.

Associated images

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Histopathology

There is no histopathology data found for Brat1.

IMPC related publications

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External links

No external links available for Brat1.

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*Brat1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Brat1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brat1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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