Atp5mk | ATP synthase membrane subunit k

GeneMGI:1891435Synonyms: Atp5md, Usmg5, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.49x10^-6
increased circulating phosphate level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.66x10^-6
increased blood urea nitrogen level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.94x10^-10
increased circulating alanine transaminase level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.67x10^-14
increased leukocyte cell number	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.95x10^-5
decreased hemoglobin content	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.56x10^-6
abnormal gait	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.76x10^-7
increased circulating amylase level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.86x10^-9
decreased circulating glucose level	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.71x10^-5
increased monocyte cell number	1 supporting dataset	Atp5mk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.67x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atp5mk.

Associated images

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Histopathology

There is no histopathology data found for Atp5mk.

IMPC related publications

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External links

No external links available for Atp5mk.

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*Atp5mk^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Atp5mk^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Atp5mk^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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