Fgf23 | fibroblast growth factor 23

GeneMGI:1891427

Physiological systems

14 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

13 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased startle reflex	1 supporting dataset	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.14x10^-6
increased freezing behavior	2 supporting datasets	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	0
decreased exploration in new environment	2 supporting datasets	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.9x10^-13
abnormal startle reflex	1 supporting dataset	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.17x10^-13
decreased locomotor activity	3 supporting datasets	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.47x10^-12
abnormal anxiety-related response	1 supporting dataset	Fgf23^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.32x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fgf23.

Associated images

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Histopathology

There is no histopathology data found for Fgf23.

IMPC related publications

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External links

No external links available for Fgf23.

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*Fgf23^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Fgf23^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell

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