Lpin2 | lipin 2

GeneMGI:1891341Synonyms: 2610511G02Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Immune system Nervous system Hematopoietic system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hydrometra	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.5x10^-5
decreased prepulse inhibition	3 supporting datasets	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.3x10^-9
preweaning lethality, incomplete penetrance	2 supporting datasets	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.15x10^-6
decreased hemoglobin content	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.72x10^-5
increased mean platelet volume	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.31x10^-12
increased red blood cell distribution width	1 supporting dataset	Lpin2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.43x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lpin2.

Associated images

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Histopathology

There is no histopathology data found for Lpin2.

IMPC related publications

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External links

No external links available for Lpin2.

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*Lpin2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lpin2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lpin2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Lpin2^{tm43131(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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