Ndufs5 | NADH:ubiquinone oxidoreductase core subunit S5

GeneMGI:1890889

Physiological systems

13 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

11 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Ndufs5^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	Ndufs5^em1(IMPC)Bay	heterozygote	Early adult	1.76x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ndufs5.

Associated images

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Histopathology

There is no histopathology data found for Ndufs5.

IMPC related publications

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External links

No external links available for Ndufs5.

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*Ndufs5^em1(IMPC)Bay*	Whole-gene deletion	‌	mouse
*Ndufs5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Ndufs5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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