Trim39 | tripartite motif-containing 39

GeneMGI:1890659Synonyms: 1100001D15Rik, Rnf23, +4 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased fasting circulating glucose level	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.34x10^-6
decreased fasting circulating glucose level	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	2.66x10^-6
absent vibrissae	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Middle aged adult	8.44x10^-7
abnormal retina morphology	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	3.55x10^-6
abnormal vibrissa morphology	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Middle aged adult	3.78x10^-9
abnormal gait	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Middle aged adult	1.32x10^-6
abnormal auditory brainstem response	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.04x10^-5
abnormal vibrissa morphology	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.28x10^-6
decreased locomotor activity	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	9.53x10^-6
increased lymphocyte cell number	1 supporting dataset	Trim39^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	4.97x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trim39.

Associated images

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Histopathology

There is no histopathology data found for Trim39.

IMPC related publications

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External links

No external links available for Trim39.

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*Trim39^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Trim39^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Trim39^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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