Panx2 | pannexin 2

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Immune system Growth/size/body region Nervous system Hematopoietic system

16 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased spleen weight1 supporting datasetPanx2tm1b(KOMP)WtsihomozygoteEarly adult8.06x10-8 
hydrometra1 supporting datasetPanx2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
enlarged uterus1 supporting datasetPanx2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased prepulse inhibition2 supporting datasetsPanx2tm1b(KOMP)WtsihomozygoteEarly adult3.57x10-6 
small superior vagus ganglion1 supporting datasetPanx2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Panx2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Panx2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Panx2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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