Suv39h2 | suppressor of variegation 3-9 2

GeneMGI:1890396Synonyms: Suv39h histone methyltransferase, KMT1B, +2 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	6.19x10^-6
increased basophil cell number	2 supporting datasets	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	9.9x10^-32
increased eosinophil cell number	2 supporting datasets	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	4.85x10^-28
increased circulating triglyceride level	1 supporting dataset	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	6.65x10^-5
increased fasting circulating glucose level	1 supporting dataset	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	9.14x10^-6
increased grip strength	1 supporting dataset	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	2.54x10^-5
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Suv39h2^{em1(IMPC)Marc}	homozygote	Early adult	3.44x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Suv39h2.

Associated images

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Histopathology

There is no histopathology data found for Suv39h2.

IMPC related publications

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External links

No external links available for Suv39h2.

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*Suv39h2^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Suv39h2^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

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