Rnf25 | ring finger protein 25

GeneMGI:1890215Synonyms: AO7, 0610009H16Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	4 supporting datasets	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.58x10^-6
abnormal lens morphology	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.24x10^-5
increased circulating cholesterol level	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.93x10^-5
increased circulating sodium level	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.75x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.58x10^-6
decreased circulating chloride level	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.7x10^-6
impaired righting response	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.77x10^-5
increased mean corpuscular volume	1 supporting dataset	Rnf25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.72x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf25.

Associated images

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Histopathology

There is no histopathology data found for Rnf25.

IMPC related publications

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External links

No external links available for Rnf25.

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*Rnf25^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rnf25^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Rnf25^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Rnf25^{tm441203(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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