Rnf25 | ring finger protein 25
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological
14 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| decreased locomotor activity | 4 supporting datasets | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.58x10-6 | ||
| abnormal lens morphology | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.24x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.93x10-5 | ||
| increased circulating sodium level | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 6.75x10-6 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.58x10-6 | ||
| decreased circulating chloride level | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.7x10-6 | ||
| impaired righting response | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.77x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Rnf25tm1.1(KOMP)Vlcg | homozygote | Early adult | 9.72x10-6 |
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| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| bone marrow | heterozygote | Section images | 100% (2/2) | 0% (0/22) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
External links
No external links available for Rnf25.
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| Rnf25tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Rnf25tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Rnf25tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Rnf25tm441203(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |