Plxnc1 | plexin C1

GeneMGI:1890127Synonyms: 2510048K12Rik, CD232, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small kidney	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	4.53x10^-5
increased circulating total protein level	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	1.35x10^-5
abnormal kidney morphology	2 supporting datasets	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating calcium level	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
increased circulating cholesterol level	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	6.12x10^-6
abnormal retina morphology	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	5.03x10^-5
small spleen	1 supporting dataset	Plxnc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plxnc1.

Associated images

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Histopathology

There is no histopathology data found for Plxnc1.

IMPC related publications

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External links

No external links available for Plxnc1.

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*Plxnc1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Plxnc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Plxnc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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