Adar | adenosine deaminase, RNA-specific
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Embryo Growth/size/body region Nervous system Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:55Adult tissues
50Embryo tissues
| decreased circulating glucose level | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.73x10-5 | ||
| abnormal neural tube closure | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| pale yolk sac | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| abnormal placenta size | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| pallor | 1 supporting dataset | Adartm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Adartm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Adar.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Adartm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Adartm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |