Crlf2 | cytokine receptor-like factor 2

GeneMGI:1889506Synonyms: Tslpr, Ly114, +1 more

Physiological systems

20 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

8 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged spleen	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged heart	1 supporting dataset	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal brain morphology	1 supporting dataset	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Crlf2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Crlf2.

Associated images

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Histopathology

There is no histopathology data found for Crlf2.

IMPC related publications

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External links

No external links available for Crlf2.

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*Crlf2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Crlf2^{tm210874(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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