Adck2 | aarF domain containing kinase 2
GeneMGI:1889336
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
16 No significant impact
6 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| abnormal motor learning | 2 supporting datasets | Adck2tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.96x10-5 | ||
| hyperactivity | 1 supporting dataset | Adck2tm1.1(KOMP)Vlcg | homozygote | Early adult | 3.9x10-5 | ||
| increased circulating potassium level | 1 supporting dataset | Adck2tm1.1(KOMP)Vlcg | homozygote | Early adult | 9.01x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| bone marrow | heterozygote | Section images | 100% (2/2) | 0% (0/22) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
Human diseases caused by Adck2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Adck2.
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