Cadm1 | cell adhesion molecule 1

GeneMGI:1889272Synonyms: RA175A, SgIGSF, +10 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Pigmentation Integument Vision/eye Behavior/neurological

17 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology2 supporting datasetsCadm1tm1a(EUCOMM)WtsihomozygoteEarly adult1.97x10-6 
abnormal behavior3 supporting datasetsCadm1tm1a(EUCOMM)WtsihomozygoteEarly adult9.74x10-7 
abnormal behavior3 supporting datasetsCadm1tm1.2BrdhomozygoteEarly adult1.06x10-7 
decreased grip strength1 supporting datasetCadm1tm1.2BrdhomozygoteEarly adult2.25x10-5 
abnormal retina pigmentation2 supporting datasetsCadm1tm1a(EUCOMM)WtsihomozygoteEarly adult2.1x10-6 
abnormal tail movements1 supporting datasetCadm1tm1a(EUCOMM)WtsihomozygoteEarly adult3.75x10-6 
abnormal skin pigmentation1 supporting datasetCadm1tm1a(EUCOMM)WtsihomozygoteEarly adult1.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cadm1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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