Rbms1 | RNA binding motif, single stranded interacting protein 1

GeneMGI:1861774Synonyms: 2600014B10Rik, MSSP-1, +3 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Growth/size/body region Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.95x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.23x10^-7
impaired glucose tolerance	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.72x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Rbms1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	7.06x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rbms1.

Associated images

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Histopathology

There is no histopathology data found for Rbms1.

IMPC related publications

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External links

No external links available for Rbms1.

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*Rbms1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Rbms1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rbms1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rbms1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Rbms1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rbms1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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