Nme6 | NME/NM23 nucleoside diphosphate kinase 6

GeneMGI:1861676Synonyms: nm23-M6, non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Nme6^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Nme6^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nme6.

Associated images

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Histopathology

There is no histopathology data found for Nme6.

IMPC related publications

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External links

No external links available for Nme6.

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*Nme6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Nme6^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Nme6^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Nme6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Nme6^{tm443943(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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