Klk4 | kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)

GeneMGI:1861379Synonyms: KLK-L1, Prss17, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Respiratory system Hematopoietic system

18 No significant impact

3 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased pulmonary ventilation2 supporting datasetsKlk4tm1.1(KOMP)VlcghomozygoteEarly adult1.39x10-6 
increased neutrophil cell number1 supporting datasetKlk4tm1.1(KOMP)VlcghomozygoteEarly adult1.6x10-5 
increased basophil cell number1 supporting datasetKlk4tm1.1(KOMP)VlcghomozygoteEarly adult1.5x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klk4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Klk4tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Klk4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Klk4tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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