Prpf40a | pre-mRNA processing factor 40A
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
7 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased erythrocyte cell number | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 2.42x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Prpf40aem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 1.37x10-28 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 9.27x10-6 | ||
| cataract | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 2.63x10-5 | ||
| increased vertical activity | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 1.92x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Prpf40aem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased hemoglobin content | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 3.68x10-7 | ||
| increased mean corpuscular volume | 1 supporting dataset | Prpf40aem1(IMPC)J | heterozygote | Early adult | 1.01x10-8 |
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External links
No external links available for Prpf40a.
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| Prpf40aem1(IMPC)J | Exon Deletion | | mouse |
| Prpf40atm380141(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |