Pck2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Digestive/alimentary
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal stomach morphology | 1 supporting dataset | Pck2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Pck2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Pck2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased circulating triglyceride level | 1 supporting dataset | Pck2em1(IMPC)Tcp | homozygote | Early adult | 2.81x10-5 | ||
| small epididymis | 1 supporting dataset | Pck2em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Pck2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pck2.
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