Snx3 | sorting nexin 3

GeneMGI:1860188Synonyms: SDP3

Physiological systems

21 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Digestive/alimentary Hematopoietic system Behavior/neurological Mortality/aging Craniofacial

9 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:22Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



spina bifida	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
exencephaly	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E18.5	N/A ^*
abnormal limb morphology	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E18.5	N/A ^*
abnormal head shape	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E18.5	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	heterozygote	Late adult	5.66x10^-5
exencephaly	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
syndactyly	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E18.5	N/A ^*
abnormal midbrain morphology	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal embryo size	1 supporting dataset	Snx3^{tm1.1(KOMP)Vlcg}	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snx3.

Associated images

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Histopathology

There is no histopathology data found for Snx3.

IMPC related publications

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External links

No external links available for Snx3.

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*Snx3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Snx3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Snx3^{tm49788(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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