Gtpbp2 | GTP binding protein 2
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Vision/eye Behavior/neurological Mortality/aging Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:41Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Gtpbp2tm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| increased exploration in new environment | 1 supporting dataset | Gtpbp2tm1b(KOMP)Mbp | homozygote | Early adult | 4.42x10-6 | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Gtpbp2tm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| hyperactivity | 1 supporting dataset | Gtpbp2tm1b(KOMP)Mbp | homozygote | Early adult | 5.38x10-9 | ||
| enlarged lymph nodes | 2 supporting datasets | Gtpbp2tm1b(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Gtpbp2tm1b(KOMP)Mbp | homozygote | Early adult | 1.44x10-6 |
| | | | | | | | | | |
External links
No external links available for Gtpbp2.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Gtpbp2tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gtpbp2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gtpbp2tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gtpbp2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |