Txnl1 | thioredoxin-like 1

GeneMGI:1860078Synonyms: TRP32, 32kDa

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	1.17x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	4.23x10^-6
decreased mean corpuscular hemoglobin	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	1.02x10^-7
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	2.92x10^-11
decreased mean corpuscular volume	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	3.16x10^-20
abnormal eyelid morphology	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	1.84x10^-6
increased monocyte cell number	2 supporting datasets	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	3.21x10^-13
decreased hematocrit	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	1.61x10^-5
increased erythrocyte cell number	1 supporting dataset	Txnl1^em1(IMPC)Tcp	homozygote	Early adult	7.07x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Txnl1.

Associated images

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Histopathology

There is no histopathology data found for Txnl1.

IMPC related publications

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External links

No external links available for Txnl1.

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*Txnl1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Txnl1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Txnl1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Txnl1^{tm440983(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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