Magix | MAGI family member, X-linked

GeneMGI:1859644Synonyms: Sfc18, Pdzx

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating creatinine level1 supporting datasetMagixem1(IMPC)HmguhomozygoteEarly adult8.29x10-5 
decreased leukocyte cell number1 supporting datasetMagixem1(IMPC)HmguhemizygoteEarly adult3.42x10-6 
decreased erythrocyte cell number1 supporting datasetMagixem1(IMPC)HmguhomozygoteEarly adult1.02x10-5 
increased mean platelet volume1 supporting datasetMagixem1(IMPC)HmguhomozygoteEarly adult9.71x10-6 
decreased erythrocyte cell number1 supporting datasetMagixem1(IMPC)HmguhemizygoteEarly adult4.7x10-6 
decreased hemoglobin content1 supporting datasetMagixem1(IMPC)HmguhemizygoteEarly adult7.57x10-6 
increased mean platelet volume1 supporting datasetMagixem1(IMPC)HmguhemizygoteEarly adult2.95x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Magixem1(IMPC)HmguExon Deletionmouse
Magixtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Magixtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Magixtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Magixtm40674(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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