Irf6 | interferon regulatory factor 6

GeneMGI:1859211Synonyms: E230028I05Rik

Physiological systems

15 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

14 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



increased circulating creatine kinase level	1 supporting dataset	Irf6^{em1(IMPC)Wtsi}	homozygote	Early adult	7.91x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Irf6^{em1(IMPC)Wtsi}	homozygote	Early adult	3.63x10^-6
increased circulating creatinine level	1 supporting dataset	Irf6^{em1(IMPC)Wtsi}	homozygote	Early adult	1.37x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Irf6.

Associated images

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Histopathology

There is no histopathology data found for Irf6.

IMPC related publications

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External links

No external links available for Irf6.

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*Irf6^{em1(IMPC)Wtsi}*	Point Mutation	‌	mouse
*Irf6^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Irf6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Irf6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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