Arl6ip1 | ADP-ribosylation factor-like 6 interacting protein 1

GeneMGI:1858943Synonyms: ARMER, AIP-6

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Behavior/neurological

16 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

hyperactivity3 supporting datasetsArl6ip1tm1b(EUCOMM)HmguhomozygoteEarly adult2.13x10-6 
abnormal retina morphology1 supporting datasetArl6ip1tm1b(EUCOMM)HmguhomozygoteEarly adult2.79x10-14 
abnormal gait1 supporting datasetArl6ip1tm1b(EUCOMM)HmguhomozygoteEarly adult8.78x10-17 
limb grasping1 supporting datasetArl6ip1tm1b(EUCOMM)HmguhomozygoteEarly adult2.52x10-11 
decreased mean corpuscular volume1 supporting datasetArl6ip1tm1b(EUCOMM)HmguhomozygoteEarly adult1.17x10-20 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arl6ip1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Arl6ip1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Arl6ip1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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