Spast | spastin

GeneMGI:1858896Synonyms: Spg4

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Nervous system

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



abnormal brain morphology	1 supporting dataset	Spast^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
hydrocephaly	1 supporting dataset	Spast^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spast.

Associated images

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Histopathology

There is no histopathology data found for Spast.

IMPC related publications

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External links

No external links available for Spast.

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*Spast^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Spast^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes