Ctps1 | cytidine 5'-triphosphate synthase 1

GeneMGI:1858304Synonyms: Ctps

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Mortality/aging Renal/urinary system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetCtps1em1(IMPC)TcpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsCtps1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetCtps1em1(IMPC)TcpheterozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetCtps1em1(IMPC)TcphomozygoteE9.5N/A * 
enlarged urinary bladder1 supporting datasetCtps1em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ctps1em1(IMPC)TcpExon Deletionmouse
Ctps1tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Ctps1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ctps1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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