Pkd2l2 | polycystic kidney disease 2-like 2

GeneMGI:1858231Synonyms: TRPP5, Polycystin - L2

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton

18 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating fructosamine level1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult1.34x10-6 
increased blood urea nitrogen level1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult1.66x10-31 
decreased fasting circulating glucose level1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult7.46x10-7 
increased circulating creatinine level1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult4.91x10-99 
decreased bone mineral density1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult1.29x10-7 
increased circulating potassium level1 supporting datasetPkd2l2tm1b(EUCOMM)WtsihomozygoteEarly adult2.04x10-16 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pkd2l2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Pkd2l2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pkd2l2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pkd2l2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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