Fbxl8 | F-box and leucine-rich repeat protein 8

GeneMGI:1354697Synonyms: FBL8

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hearing/vestibular/ear Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased monocyte cell number	1 supporting dataset	Fbxl8^{em2(IMPC)Marc}	homozygote	Early adult	8.4x10^-8
abnormal auditory brainstem response	1 supporting dataset	Fbxl8^{em2(IMPC)Marc}	homozygote	Early adult	8.75x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Fbxl8.

Associated images

Loading...

Histopathology

There is no histopathology data found for Fbxl8.

IMPC related publications

Loading...

External links

No external links available for Fbxl8.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Fbxl8^{em2(IMPC)Marc}*	Deletion	‌	mouse
*Fbxl8^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Fbxl8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fbxl8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Fbxl8^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes