Zfp503 | zinc finger protein 503

GeneMGI:1353644Synonyms: Nolz1, Zpo2, +3 more

Physiological systems

22 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system Craniofacial Renal/urinary system

9 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal optic disk morphology	1 supporting dataset	Zfp503^em1(IMPC)Mbp	heterozygote	Early adult	1.96x10^-13
abnormal placenta vasculature	1 supporting dataset	Zfp503^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
enlarged lymph nodes	2 supporting datasets	Zfp503^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Zfp503^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Zfp503^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	Zfp503^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
increased exploration in new environment	1 supporting dataset	Zfp503^em1(IMPC)Mbp	heterozygote	Early adult	1.08x10^-5
edema	1 supporting dataset	Zfp503^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
microcephaly	1 supporting dataset	Zfp503^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Zfp503^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp503.

Associated images

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Histopathology

There is no histopathology data found for Zfp503.

IMPC related publications

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External links

No external links available for Zfp503.

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*Zfp503^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Zfp503^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zfp503^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zfp503^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Zfp503^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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