Lcmt1 | leucine carboxyl methyltransferase 1
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging
12 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased spleen weight | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | heterozygote | Late adult | 9.66x10-5 | ||
| abnormal heart morphology | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | heterozygote | Late adult | N/A * | ||
| abnormal circulating phosphate level | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | heterozygote | Late adult | 1.75x10-5 | ||
| increased large unstained cell number | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | heterozygote | Late adult | 1.72x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | homozygote | Early adult | N/A * | ||
| abnormal locomotor activation | 1 supporting dataset | Lcmt1em1(IMPC)Rbrc | heterozygote | Late adult | 8.53x10-5 |
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External links
No external links available for Lcmt1.
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| Lcmt1em1(IMPC)Rbrc | Exon Deletion | | mouse |
| Lcmt1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Lcmt1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |