Baz1b | bromodomain adjacent to zinc finger domain, 1B

GeneMGI:1353499Synonyms: Wbscr9, WSTF

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating cholesterol level1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult2.03x10-9 
decreased circulating HDL cholesterol level1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult5.45x10-7 
decreased body weight1 supporting datasetBaz1btm2a(KOMP)WtsihomozygoteEarly adult2.74x10-11 
decreased body weight1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult9.45x10-7 
preweaning lethality, incomplete penetrance1 supporting datasetBaz1btm2a(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating chloride level1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult1.58x10-5 
abnormal startle reflex1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult5.1x10-5 
decreased circulating total protein level1 supporting datasetBaz1btm2a(KOMP)WtsiheterozygoteEarly adult5.63x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Baz1btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Baz1btm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Baz1btm3a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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