Mlh3 | mutL homolog 3

GeneMGI:1353455

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Reproductive system

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



female infertility	1 supporting dataset	Mlh3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Mlh3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mlh3.

Associated images

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Histopathology

There is no histopathology data found for Mlh3.

IMPC related publications

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External links

No external links available for Mlh3.

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*Mlh3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Mlh3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Mlh3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mlh3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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