Gulo | gulonolactone (L-) oxidase
Physiological systems
22 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system
14 No significant impact
2 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating cholesterol level | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | 1.03x10-5 | ||
| abnormal heart morphology | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| anophthalmia | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | 3.04x10-5 | ||
| enlarged heart | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | 4.8x10-5 | ||
| enlarged spleen | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal optic disk morphology | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | 5.5x10-5 | ||
| abnormal spleen morphology | 1 supporting dataset | Guloem1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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External links
No external links available for Gulo.
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| Guloem1(IMPC)Ccpcz | Exon Deletion | | mouse |