Scmh1 | sex comb on midleg homolog 1
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Digestive/alimentary Hearing/vestibular/ear Liver/biliary system Cardiovascular system
17 No significant impact
3 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| thin ventricular wall | 1 supporting dataset | Scmh1tm1e.1(EUCOMM)Hmgu | homozygote | Late adult | 7.62x10-5 | ||
| enlarged cecum | 1 supporting dataset | Scmh1tm1e.1(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Scmh1tm1e.1(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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Human diseases caused by Scmh1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Scmh1.
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| Scmh1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Scmh1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Scmh1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell mouse |
| Scmh1tm1e.1(EUCOMM)Hmgu | Promoter excision from Targeted, non-conditional allele | | mouse |