Scmh1 | sex comb on midleg homolog 1

GeneMGI:1352762Synonyms: Scml3

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Digestive/alimentary Hearing/vestibular/ear Liver/biliary system Cardiovascular system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

thin ventricular wall1 supporting datasetScmh1tm1e.1(EUCOMM)HmguhomozygoteLate adult7.62x10-5 
enlarged cecum1 supporting datasetScmh1tm1e.1(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetScmh1tm1e.1(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scmh1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Scmh1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Scmh1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
mouse
Scmh1tm1e.1(EUCOMM)HmguPromoter excision from Targeted, non-conditional allelemouse

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