Hdgfl3 | HDGF like 3

GeneMGI:1352760Synonyms: Hdgfrp3, HRP-3, +1 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Integument Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



hyperactivity	5 supporting datasets	Hdgfl3^em1(IMPC)Tcp	homozygote	Early adult	1.8x10^-7
decreased body length	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	4.44x10^-5
increased exploration in new environment	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Middle aged adult	9.32x10^-5
enlarged urinary bladder	2 supporting datasets	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
decreased bone mineral content	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	6.75x10^-6
decreased lean body mass	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	1.01x10^-5
decreased grip strength	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Early adult	3.56x10^-5
decreased grip strength	2 supporting datasets	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	1.46x10^-7
increased exploration in new environment	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Late adult	7.71x10^-9
abnormal eye morphology	1 supporting dataset	Hdgfl3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hdgfl3.

Associated images

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Histopathology

There is no histopathology data found for Hdgfl3.

IMPC related publications

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External links

No external links available for Hdgfl3.

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*Hdgfl3^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Hdgfl3^{tm114221(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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