Iqgap1 | IQ motif containing GTPase activating protein 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| short tibia | 1 supporting dataset | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.54x10-16 | ||
| increased grip strength | 2 supporting datasets | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.69x10-6 | ||
| decreased bone mineral density | 1 supporting dataset | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.79x10-6 | ||
| increased lymphocyte cell number | 1 supporting dataset | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.52x10-14 | ||
| increased leukocyte cell number | 1 supporting dataset | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.65x10-11 | ||
| decreased exploration in new environment | 1 supporting dataset | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.94x10-5 |
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External links
No external links available for Iqgap1.
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| Iqgap1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Iqgap1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Iqgap1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |