Cabp1 | calcium binding protein 1

GeneMGI:1352750Synonyms: caldendrin

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

increased monocyte cell number2 supporting datasetsCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult1.07x10-5 
abnormal coat appearance1 supporting datasetCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult7.06x10-6 
increased spleen weight1 supporting datasetCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult9.98x10-5 
decreased locomotor activity5 supporting datasetsCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult4.76x10-5 
decreased total body fat amount1 supporting datasetCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult3.19x10-5 
increased neutrophil cell number2 supporting datasetsCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult3.84x10-28 
decreased exploration in new environment1 supporting datasetCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult9.91x10-6 
decreased lymphocyte cell number1 supporting datasetCabp1tm1b(EUCOMM)WtsihomozygoteEarly adult2.3x10-24 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cabp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cabp1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cabp1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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