Cabp2 | calcium binding protein 2

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Pigmentation Integument Hearing/vestibular/ear Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetCabp2em1(IMPC)JhomozygoteEarly adult7.09x10-8 
abnormal vocalization1 supporting datasetCabp2em1(IMPC)JhomozygoteEarly adult2.42x10-10 
abnormal auditory brainstem response5 supporting datasetsCabp2em1(IMPC)JhomozygoteEarly adult2.17x10-14 
decreased grip strength1 supporting datasetCabp2em1(IMPC)JhomozygoteEarly adult1.34x10-5 
decreased startle reflex1 supporting datasetCabp2em1(IMPC)JhomozygoteEarly adult1.8x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cabp2em1(IMPC)JExon Deletionmouse
Cabp2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cabp2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Cabp2tm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cabp2tm2e(KOMP)MbpTargeted, non-conditional alleleES Cell
Cabp2tm92183(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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