Stau2 | staufen double-stranded RNA binding protein 2
GeneMGI:1352508
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton
15 No significant impact
3 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased hematocrit | 1 supporting dataset | Stau2em1(IMPC)Mbp | homozygote | Early adult | 4.94x10-5 | ||
| increased hemoglobin content | 1 supporting dataset | Stau2em1(IMPC)Mbp | homozygote | Early adult | 1.42x10-5 | ||
| increased total body fat amount | 2 supporting datasets | Stau2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.19x10-5 | ||
| increased erythrocyte cell number | 1 supporting dataset | Stau2em1(IMPC)Mbp | homozygote | Early adult | 2.18x10-5 | ||
| decreased lean body mass | 1 supporting dataset | Stau2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.8x10-5 | ||
| decreased body length | 1 supporting dataset | Stau2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 7.28x10-5 | ||
| hyperactivity | 1 supporting dataset | Stau2em1(IMPC)Mbp | homozygote | Early adult | 9.37x10-5 | ||
| increased vertical activity | 1 supporting dataset | Stau2em1(IMPC)Mbp | homozygote | Early adult | 2.48x10-5 | ||
| decreased bone mineral content | 2 supporting datasets | Stau2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.92x10-5 | ||
| increased monocyte cell number | 2 supporting datasets | Stau2em1(IMPC)Mbp | homozygote | Early adult | 1.54x10-5 |
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Human diseases caused by Stau2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Stau2.
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| Stau2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Stau2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Stau2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |