Stau2 | staufen double-stranded RNA binding protein 2

GeneMGI:1352508

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



increased hematocrit	1 supporting dataset	Stau2^em1(IMPC)Mbp	homozygote	Early adult	4.94x10^-5
increased hemoglobin content	1 supporting dataset	Stau2^em1(IMPC)Mbp	homozygote	Early adult	1.42x10^-5
increased total body fat amount	2 supporting datasets	Stau2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.19x10^-5
increased erythrocyte cell number	1 supporting dataset	Stau2^em1(IMPC)Mbp	homozygote	Early adult	2.18x10^-5
decreased lean body mass	1 supporting dataset	Stau2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.8x10^-5
decreased body length	1 supporting dataset	Stau2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.28x10^-5
hyperactivity	1 supporting dataset	Stau2^em1(IMPC)Mbp	homozygote	Early adult	9.37x10^-5
increased vertical activity	1 supporting dataset	Stau2^em1(IMPC)Mbp	homozygote	Early adult	2.48x10^-5
decreased bone mineral content	2 supporting datasets	Stau2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.92x10^-5
increased monocyte cell number	2 supporting datasets	Stau2^em1(IMPC)Mbp	homozygote	Early adult	1.54x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stau2.

Associated images

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Histopathology

There is no histopathology data found for Stau2.

IMPC related publications

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External links

No external links available for Stau2.

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*Stau2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Stau2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Stau2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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