Bcar3 | breast cancer anti-estrogen resistance 3

GeneMGI:1352501Synonyms: AND-34

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

13 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating insulin level1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adult6.01x10-5 
decreased body length1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adult9.17x10-5 
cataract1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adult1.83x10-5 
increased basophil cell number2 supporting datasetsBcar3em1(IMPC)MbphomozygoteEarly adult1.07x10-5 
abnormal kidney morphology1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating calcium level1 supporting datasetBcar3em1(IMPC)MbphomozygoteEarly adult3.89x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bcar3em1(IMPC)MbpExon Deletionmouse
Bcar3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bcar3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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