Bcar3 | breast cancer anti-estrogen resistance 3
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system
13 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating insulin level | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | 6.01x10-5 | ||
| decreased body length | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | 9.17x10-5 | ||
| cataract | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | 1.83x10-5 | ||
| increased basophil cell number | 2 supporting datasets | Bcar3em1(IMPC)Mbp | homozygote | Early adult | 1.07x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased circulating calcium level | 1 supporting dataset | Bcar3em1(IMPC)Mbp | homozygote | Early adult | 3.89x10-6 |
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Human diseases caused by Bcar3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Bcar3.
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| Bcar3em1(IMPC)Mbp | Exon Deletion | | mouse |
| Bcar3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Bcar3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |