Bag3 | BCL2-associated athanogene 3

GeneMGI:1352493Synonyms: Bis, Bcl-2-interacting death suppressor

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

20 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased blood urea nitrogen level	1 supporting dataset	Bag3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.95x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Bag3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bag3.

Associated images

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Histopathology

There is no histopathology data found for Bag3.

IMPC related publications

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External links

No external links available for Bag3.

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*Bag3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bag3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bag3^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Bag3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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