Nr0b1 | nuclear receptor subfamily 0, group B, member 1

GeneMGI:1352460Synonyms: Ahch, DAX-1, +3 more

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Hematopoietic system Skeleton

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating LDL cholesterol level	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	4.2x10^-5
increased hemoglobin content	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	2.25x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	2.36x10^-12
increased circulating serum albumin level	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	5.09x10^-5
increased circulating magnesium level	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	3.86x10^-5
abnormal reproductive system morphology	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	2.54x10^-22
increased circulating iron level	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	7.63x10^-5
increased bone mineral content	1 supporting dataset	Nr0b1^{em2(IMPC)Wtsi}	hemizygote	Early adult	2.19x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nr0b1.

Associated images

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Histopathology

There is no histopathology data found for Nr0b1.

IMPC related publications

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External links

No external links available for Nr0b1.

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*Nr0b1^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Nr0b1^{em2(IMPC)Wtsi}*	Exon Deletion	‌	mouse

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