Cxcl9 | C-X-C motif chemokine ligand 9

GeneMGI:1352449Synonyms: crg-10, CMK, +2 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased lymphocyte cell number	1 supporting dataset	Cxcl9^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.34x10^-5
increased circulating cholesterol level	1 supporting dataset	Cxcl9^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.72x10^-5
decreased neutrophil cell number	2 supporting datasets	Cxcl9^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.45x10^-8
decreased fasting circulating glucose level	1 supporting dataset	Cxcl9^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.22x10^-14
increased circulating HDL cholesterol level	1 supporting dataset	Cxcl9^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.17x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cxcl9.

Associated images

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Histopathology

There is no histopathology data found for Cxcl9.

IMPC related publications

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External links

No external links available for Cxcl9.

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*Cxcl9^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cxcl9^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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