Slco1b2 | solute carrier organic anion transporter family, member 1b2

GeneMGI:1351899Synonyms: Oatp1b2, mlst-1, +3 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Vision/eye

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetSlco1b2em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating bilirubin level1 supporting datasetSlco1b2em1(IMPC)MbphomozygoteEarly adult2.58x10-125 
abnormal skin morphology1 supporting datasetSlco1b2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slco1b2em1(IMPC)MbpInsertion, Intragenic deletionmouse
Slco1b2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slco1b2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slco1b2tm44016(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Slco1b2tm44016(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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