Abcc5 | ATP-binding cassette, sub-family C member 5

GeneMGI:1351644Synonyms: Abcc5a, Mrp5, +2 more

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased lymphocyte cell number	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	1.03x10^-6
increased blood urea nitrogen level	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	3.02x10^-5
decreased circulating glucose level	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	2.74x10^-8
impaired glucose tolerance	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	2.61x10^-5
limb grasping	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	5.69x10^-7
increased startle reflex	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	6.78x10^-9
decreased leukocyte cell number	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	1.33x10^-6
decreased circulating calcium level	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	4.47x10^-5
decreased eosinophil cell number	1 supporting dataset	Abcc5^em1(IMPC)H	homozygote	Early adult	4.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abcc5.

Associated images

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Histopathology

There is no histopathology data found for Abcc5.

IMPC related publications

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External links

No external links available for Abcc5.

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*Abcc5^em1(IMPC)H*	Exon Deletion	‌	mouse
*Abcc5^em2(IMPC)H*	Exon Deletion	‌	mouse
*Abcc5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Abcc5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Abcc5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Abcc5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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